Risk factors for premature mortality in patients with diabetic foot ulcers: a one-year retrospective study from a multidisciplinary clinic
DOI:
https://doi.org/10.15277/bjd.2026.506Keywords:
diabetic foot ulcer, premature mortality, smoking, cardiovascular diseaseAbstract
Background: Diabetic foot ulcers (DFUs) are associated with high morbidity and mortality. This study examined factors associated with earlier death in patients managed within a multidisciplinary foot clinic.
Methods: We performed a retrospective study of 138 patients with DFUs who died in the year 2024. Cause of death assessed through Medical Certificate of Cause of Death (MCCD). Complementary multivariable linear and logistic regression analyses were used to identify factors associated with younger age at death and premature mortality (age < 70 years).
Results: Cardiovascular disease was the leading cause of death (28.3%). Smoking, poor glycaemic control, renal replacement therapy, and prior lower-limb amputation were independently associated with premature mortality, while prior revascularisation was associated with lower odds of early death.
Conclusion: Patients with DFUs who are actively smoking with adverse severity markers are at high risk of premature death. Multidisciplinary foot clinic should also include cardiovascular risk optimisation.
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