AGP in daily clinical practice: a guide for use with the FreeStyle Libre flash glucose monitoring system

Authors

  • Fraser W Gibb Edinburgh Centre for Endocrinology and Diabetes, Edinburgh, UK
  • Peter Jennings University Hospitals of Derby and Burton NHS FT, Derby, UK. Nottingham Trent University School of Social Sciences, Shakespeare Street, Nottingham, UK
  • Lalantha Leelarathna Manchester Diabetes Centre, Manchester University NHS Foundation Trust & University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
  • Emma G Wilmot University Hospitals of Derby and Burton NHS FT, Derby, UK.

DOI:

https://doi.org/10.15277/bjd.2020.240

Keywords:

ambulatory glucose profile, AGP, continuous glucose monitoring, flash glucose monitoring, CGM, glycaemic control, glycaemic variability, glycaemic stability, hypoglycaemia, hyperglycaemia

Abstract

As real-time continuous glucose monitoring and flash glucose monitoring systems become more widely prescribed in the daily management of diabetes, it is important that the ambulatory glucose profile (AGP) methodology for reviewing and interpreting trends in glucose control is effectively applied. In this article we look at the essential features of the AGP and provide systematic and practical guidance on how the AGP can be interpreted in daily diabetes care with confidence. Using examples taken from glucose data captured by the FreeStyle Libre flash glucose monitoring system, we show how each aspect of the AGP can be used to understand daily patterns in glucose control for a person with diabetes, including the importance of time in range and adjunct use of individual daily logs. Using these elements collectively, we show how and why treatment adjustments can be made, with the goal of improving glycaemic control and diabetes outcomes.

Author Biographies

Fraser W Gibb, Edinburgh Centre for Endocrinology and Diabetes, Edinburgh, UK

Consultant Endocrinologist

Honorary Clinical Senior Lecturer, University of Edinburgh

Peter Jennings, University Hospitals of Derby and Burton NHS FT, Derby, UK. Nottingham Trent University School of Social Sciences, Shakespeare Street, Nottingham, UK

Diabetes Specialist Nurse, University Hospitals of Derby and Burton NHS Foundation Trust. Senior Lecturer, Nottingham Trent University

Lalantha Leelarathna, Manchester Diabetes Centre, Manchester University NHS Foundation Trust & University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK

Consultant Diabetologist and Honorary Senior Lecturer at Manchester Diabetes Centre, Manchester Royal Infirmary

Emma G Wilmot, University Hospitals of Derby and Burton NHS FT, Derby, UK.

Consultant Diabetologist at University Hospitals of Derby and Burton and Honorary (consultant) Assistant Professor at the University of Nottingham

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Published

2020-06-05

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Section

Learning from practice

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