Diabetes should not dissuade arteriovenous fistula formation


  • Andrew C Gordon West London Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, UK
  • Sham Dholakia West London Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, UK
  • Damien Ashby West London Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, UK
  • Jeremy s Crane West London Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, UK




diabetes, arteriovenous, fistula formation, dialysis


Background: Fistula maturation is a complex multifactorial process with the effect of diabetes on vessel augmentation during fistula formation remaining unclear. Variation in results has reflected in a range of clinical practice with regard to patient selection and fistula formation and so requires more study. The aim of our study was to compare outcomes of diabetic and non-diabetic patients undergoing formation of a new upper limb arteriovenous fistula (AVF) to assess whether diabetes has a prognostic effect on outcome.

Methods: A retrospective cohort study analysing 339 patients looking at both radiocephalic and brachiocephalic fistula formation in diabetic and non-diabetic patients was designed, with the primary outcome being fistula failure and then time taken to mature.

Results: No difference was found between diabetic and non-diabetic patients in terms of fistula failure or time to mature.

Conclusions: With AVF remaining the best access for dialysis, diabetic patients should not be discouraged from being offered AVF formation as they have equivalent outcomes to non-diabetic patients.


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Original Research