Glucose infusion-induced liver dysfunction following treatment of prolonged hypoglycaemia after a massive insulin overdose

Authors

  • Zaka Haq Kings College Hospital London, London, UK
  • Mamta Joshi Kings College Hospital London, London, UK
  • Sonya Ghatahora Brighton and Sussex University Hospitals, Brighton, UK
  • Michael Okorie Brighton and Sussex University Hospitals, Brighton, UK Brighton and Sussex Medical School Brighton, UK

DOI:

https://doi.org/10.15277/bjdvd.2015.048

References

Jordan H. Unusual sequel of large overdose of insulin. BMJ 1946;1:276. http://dx.doi.org/10.1136/bmj.1.4442.276

Eldred AE, Mustafa OG, Hunt KF, Whitelaw C. Problem based review: the patient who has taken an overdose of long-acting insulin analogue. Acute Med 2013;12:167-72.

Tofade TS, Liles EA. Intentional overdose with insulin glargine and insulin aspart. Pharmacotherapy 2004;24:1412-18. http://dx.doi.org/10.1592/phco.24.14.1412.43147

Warriner D, Debono M, Gandhi RA, et al. Acute hepatic injury following treatment of a long-acting insulin analogue overdose necessitating urgent insulin depot excision. Diabet Med 2012;29:232-5. http://dx.doi.org/10.1111/j.1464-5491.2011.03385.x

Gillies PS, Figgitt DP, Lamb HM. Insulin glargine. Drugs 2000;59:253-60. http://dx.doi.org/10.2165/00003495-200059020-00009

Groth CM, Banzon ER. Octreotide for the treatment of hypoglycemia after insulin glargine overdose. J Emerg Med 2013;45:194-8. http://dx.doi.org/10.1016/j.jemermed.2012.11.099

Joint British Diabetes Societies. The Hospital Management of Hypoglycaemia in Adults with Diabetes Mellitus. Revised September 2013. Available from: http://www.diabetologists-abcd.org.uk/subsite/JBDS_IP_ Hypo_Adults_Revised.pdf.

Tsujimoto T, Takano M, Nishiofuku M, et al. Rapid onset of glycogen storage hepatomegaly in a type-2 diabetic patient after a massive dose of long-acting insulin and large doses of glucose. Intern Med 2006;45:469-73. http://dx.doi.org/10.2169/internalmedicine.45.1548

Jolliet P, Leverve X, Pichard C. Acute hepatic steatosis complicating massive insulin overdose and excessive glucose administration. Intensive Care Med 2001;27:313-16. http://dx.doi.org/10.1007/s001340000763

Mumtaz K, Azam Z, Hamid S, et al. Role of N-acetylcysteine in adults with non-acetaminophen-induced acute liver failure in a center without the facility of liver transplantation. Hepatol Int 2009;3:563-70. http://dx.doi.org/10.1007/s12072-009-9151-0

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Published

2015-12-10

Issue

Vol. 15 No. 4 (2015)

Section

Case Reports

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