Association of British Clinical Diabetologists (ABCD) and Renal Association clinical guidelines: Hypertension management and renin-angiotensin-aldosterone system blockade in patients with diabetes, nephropathy and/or chronic kidney disease

Indranil Dasgupta, Debasish Banerjee, Tahseen A Chowdhury, Parijat De, Mona Wahba, Stephen Bain, Andrew Frankel, Damian Fogarty, Ana Pokrajac, Peter H Winocour

Abstract


Diabetes is the commonest cause of end-stage renal disease; over a quarter of patients who are on dialysis in the UK have diabetes. Diabetic kidney disease is associated with high cardiovascular morbidity and mortality. Hypertension is a modifiable risk factor for cardiovascular complications and progression of diabetic kidney disease.

The Association of British Clinical Diabetologists and the Renal Association have jointly developed guidelines for management of hypertension through different stages of diabetic kidney disease. Here we present a summary of clinical practice recommendations, audit standards, and areas that require further research.


Keywords


diabetes, blood pressure, albuminuria, chronic, kidney disease, dialysis

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References


Ritz E, Orth SR. Nephropathy in patients with type 2 diabetes mellitus. N Engl J Med 1999;341:1127–33. https://doi.org/10.1056/NEJM199910073411506

Gilg J, Caskey F, Fogarty D. UK Renal Registry 18th Annual Report: Chapter 1 UK Renal Replacement Therapy Incidence in 2014: National and Centre-specific Analyses. Nephron 2016;132(Suppl 1):9–40. https://doi.org/10.1159/000444815

Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993;16:434–44. https://doi.org/10.2337/diacare.16.2.434




DOI: https://doi.org/10.15277/bjd.2017.152

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The Journal of the Association of British Clinical Diabetologists