Sanger, Hodgkin, Yalow and the impact of insulin analogues

Authors

  • David Russell - Jones University of Surrey and Royal Surrey Foundation Trust

DOI:

https://doi.org/10.15277/bjd.2022.361

Keywords:

insulin analogues, insulin structure, insulin treatment

References

Fralick M, Zinman B. The discovery of insulin in Toronto: beginning a 100 year journey of research and clinical achievement. Diabetologia 2021; 64:947–53. https://doi.org/10.1007/s00125-020-05371-6

Ryle AP, Sanger F, Smith LF, Kitai R. The disulphide bonds of insulin. Biochem J 1955;60:541–56. https://doi.org/10.1042/bj0060541

Hodgkin DC. The Banting Memorial Lecture. The structure of insulin. Diabetes 1972;21:1131-50. https://doi.org/10.2337/diab.21.12.1131

Yalow RS, Berson SA. Immunoassay of endogenous plasma insulin in man. J Clin Invest 1960;39:1157-73. https://doi.org/10.1172/JCI104130

Herring R, Russell-Jones DL. Lessons for modern insulin development. Diabet Med 2018;35(10):1320–8. https://doi.org/10.1111/dme.13692

Herring R, Jones RH, Russell-Jones DL. Hepatoselectivity and the evolution of insulin. Diabetes Obesity Metabolism 2014;16(1):1-8. https://doi.org/10.1111/dom.12117

Russell-Jones D, Herring R. 100 years of physiology, discrimination and won- der. Diabet Med 2021;38:e14642. https://doi.org/10.1111/dme.14642

Downloads

Published

2022-12-22